872 research outputs found

    Memory Protection in a Real-Time Operating System

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    During the last years the number of Electrical Control Units (ECU) in vehicles have increased rapidly with the effect of increasing costs. To meet this trend and reduce costs, applications have to be centralized into more powerful ECUs. This gives rise to new problems such as data and temporal integrity. The thesis gives an introduction to these new problems and a solution based on static time-triggered scheduling combined with memory protection. Memory protection mechanisms and hardware are evaluated, resulting in the recommendation of a platform. The thesis also propose modification and extensions to a real-time operating system used today within the Volvo Group. The work has been conducted at Volvo Technology (VTEC) in Gothenburg. VTEC is a combined research and consulting company within the Volvo Grou

    Vasoactive intestinal peptide induces cell cycle arrest and regulatory functions in human T cells at multiple levels

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    Vasoactive intestinal peptide (VIP) is a potent anti-inflammatory neuropeptide that, by inhibiting Th1-driven responses and inducing the emergence of regulatory T cells (Treg), has been proven successful in the induction of tolerance in various experimental models of autoimmune disorders. Here, we investigate the molecular mechanisms involved in VIP-induced tolerance. VIP treatment in the presence of T-cell receptor (TCR) signaling and CD28 costimulation induced cell cycle arrest in human T cells. VIP blocked G1/S transition and inhibited the synthesis of cyclins D3 and E and the activation of the cyclin-dependent kinases (CDKs) cdk2 and cdk4. This effect was accompanied by maintenance of threshold levels of the CDK inhibitor p27kip1 and impairment of phosphatidylinositol 3-kinase (PI3K)-Akt signaling. Inhibition of interleukin 2 (IL-2) transcription and downregulation of signaling through NFAT, AP-1, and Ras-Raf paralleled the VIPinduced cell cycle arrest. Noteworthy from a functional point of view is the fact that VIP-treated T cells show a regulatory phenotype characterized by high expression of CD25, cytotoxic-T-lymphocyte-associated protein 4 (CTLA4), and Forkhead box protein 3 (FoxP3) and potent suppressive activities against effector T cells. CTLA4 appears to be critically involved in the generation and suppressive activities of VIP-induced Treg. Finally, cyclic AMP (cAMP) and protein kinase A (PKA) activation seems to mediate the VIP-induced cell cycle arrest and Treg generation

    The effect of the tailbiting restriction on feedback encoders

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    It is shown that, for short and moderate relative tailbiting lengths and high signal-to-noise ratios, systematic feedback encoders have better bit error performance than nonsystematic feedforward encoders. Conditions for when tailbiting will fail are given and it is described how the encoder starting state can be obtained for feedback encoders in both controller and observer canonical for

    New tailbiting encoders

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    In B tailbiting trellis encoder, the starting state of the encoder is set to the state at which the machine will be at the end of the encoded frame. By this means the probability of decoding error at the end of the frame can be kept low without the addition of termination bits and the consequent rate loss. We report on an extensive search for short and moderatelength convoluticinal encoders for tailbiting trellis representations of bllock codes at rates 1/4, 1/3, 1/2, and 2/3. The short tailbiting representations found are typically as good as the best known block codes

    Finger Number and Device Performance: A Case Study of Reduced Graphene Oxide Microsupercapacitors

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    Microsupercapacitors (MSCs) are recognized as suitable energy storage devices for the internet of things (IoTs) applications. Herein is described the work conducted to assess the areal energy and power densities of MSCs with 2, 10, 20, and 40 interdigital finger electrodes on a fixed device footprint area (the finger interspacing is fixed at 40 μm, and the finger width and length are allowed to vary to fit the footprint area). The MSCs are based on reduced graphene oxide (rGO) materials and fabricated with a spin-coating and etch method. The performance evaluation indicates a strong dependency of areal capacitance and energy density on the number of fingers, and the maximum (impedance match) power density is also influenced to a relatively large extent, whereas the average power density is not sensitive to the configuration parameters in the present evaluation settings (scan rate 20–200 mV s−1 and current density of 100 μA cm−2). For the rGO-based devices, the equivalent distributed resistance may play an important role in determining the device resistance and power-related performance

    Functional ecology of aquatic phagotrophic protists - Concepts, limitations, and perspectives

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    Special issue Current trends in protistology – results from the VII ECOP - ISOP Joint Meeting 2015.-- 25 pages, 6 figures, 1 tableFunctional ecology is a subdiscipline that aims to enable a mechanistic understanding of patterns and processes from the organismic to the ecosystem level. This paper addresses some main aspects of the process-oriented current knowledge on phagotrophic, i.e. heterotrophic and mixotrophic, protists in aquatic food webs. This is not an exhaustive review; rather, we focus on conceptual issues, in particular on the numerical and functional response of these organisms. We discuss the evolution of concepts and define parameters to evaluate predator–prey dynamics ranging from Lotka–Volterra to the Independent Response Model. Since protists have extremely versatile feeding modes, we explore if there are systematic differences related to their taxonomic affiliation and life strategies. We differentiate between intrinsic factors (nutritional history, acclimatisation) and extrinsic factors (temperature, food, turbulence) affecting feeding, growth, and survival of protist populations. We briefly consider intraspecific variability of some key parameters and constraints inherent in laboratory microcosm experiments. We then upscale the significance of phagotrophic protists in food webs to the ocean level. Finally, we discuss limitations of the mechanistic understanding of protist functional ecology resulting from principal unpredictability of nonlinear dynamics. We conclude by defining open questions and identifying perspectives for future research on functional ecology of aquatic phagotrophic protistsHA was supported by grants from the German Research Foundation (DFG; AR 288/16) and from the Federal Ministry for Education and Research (BMBF: 03G0237B; 02WRM1364D). Project FERMI (CGL2014-59227-R) was awarded to AC from the Spanish Ministry of Economy and Competitiveness. RA was supported by the the European Union's Horizon 2020 research and innovation programme (Marie Sklodowska-Curie grant agreement No 658882). PJH was supported by the Danish Council for independent Reseach, project DDF-4181-00484. TW was financially supported by the Austrian Science Fund (FWF, projects P20118-B17 and P20360-B17). DJSM received no support for his efforts on this study, other than his salary provided by the University of LiverpoolPeer Reviewe

    Investigation of vertical carbon nanosheet growth and its potential for microsupercapacitors

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    One of the biggest applications that are coming with the Internet of Things (IoT) are miniaturized sensor networks that connect wirelessly to each other and the internet. Microsupercapacitors (MSCs) are ideal to power these devices, with large cyclability and lifetime. Porous carbons are the material of choice for these devices, but their morphology and manufacturing are far from optimized. Vertically oriented graphene MSCs have shown great promise due to their high specific surface areas and conductivity. In this work, the growth of vertically aligned carbon nanosheets (CNS) on 2-inch wafers has been studied, and it has been used as active material to manufacture MSC and transmission line model (TLM) wafers. The fabricated CNS MSC devices show a capacitance of 7.4 ?F (50.7 ?F/cm2, normalized to the area of the electrodes), a five-times increase from previous results obtained by the group
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